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KMID : 0616120180490030189
Korean Journal of Pharmacognosy
2018 Volume.49 No. 3 p.189 ~ p.202
Biological Activities of Phloroglucinols and Prenylated Flavonoids from Humuli Strobilus
Kim Hyun-Jung

Yoon Goo
Cho Young-Chang
Lee Ik-Soo
Kang Bok-Yun
Abstract
Hop cones (Humuli Strobili) are the female inflorescences of hop plants (Humulus lupulus L.) belonging to the family Cannabaceae. They have been used as herbal remedies to treat mood and sleep disturbances, and mainly to add as a bittering ingredient in brewing process. Considerable interests on pharmacological and biological activities of hop cones have been focused on their major constituents, namely, phloroglucinols (humulone, lupulone), terpenes (myrcene, humulene), and prenylated flavonoids (xanthohumol, isoxanthohumol, 6-prenylnaringenin, and 8-prenylnaringenin). The present review describes and discusses biological activity profiles of these major compounds in the hop cones.
KEYWORD
Humulus lupulus, Phloroglucinols, Prenylated flavonoids, Biological activity
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